Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ CMP-Sialic Acid, Disodium Salt InSolution™
A 25 mM (10 mg/608 μL) sterile-filtered solution of CMP-Sialic Acid, Disodium Salt in H2O.
MilliporeSigma™ Calbiochem™ Opn4 Antagonist
Prevents melanopsin/Opn4 photoactivation in a reversible manner. Inhibits cellular phototransduction mediated by human Opn4 (IC50 = 665 nM; using CHO transfectants).
MilliporeSigma™ Calbiochem™ 1,2-Dioctanoyl-sn-glycerol
Cell-permeable activator of protein kinase C (PKC).
MilliporeSigma™ Calbiochem™ 2',5'-Dideoxyadenosine
Cell-permeable, non-competitive adenylate cyclase inhibitor (IC50 = 3 μM), that binds to the adenosine P1 binding site.
MilliporeSigma™ Calbiochem™ Akt Inhibitor VIII, Isozyme-Selective, Akti-1/2
Akt Inhibitor VIII, Isozyme-Selective, Akti-1/2, CAS 612847-09-3, is a cell-permeable, reversible inhibitor of Akt1/Akt2 (IC50 = 58 nM, 210 nM, & 2.12 μM for Akt1, Akt2, and Akt3, respectively).
MilliporeSigma™ Calbiochem™ InSolution™ AMPK Inhibitor, Compound C·2HCl
The InSolution™ AMPK Inhibitor, Compound C·2HCl, also referenced under CAS 866405-64-3, controls the biological activity of AMPK. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ p-APMSF, Hydrochloride
Alternative to DFP and PMSF.
MilliporeSigma™ Calbiochem™ PKD Inhibitor, CID755673
The PKD Inhibitor, CID755673, also referenced under CAS 521937-07-5, controls the biological activity of PKD. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ HIF Prolyl Hydroxylase Inhibitor
A cell-permeable, hydroxyquinoline HIF Prolyl Hydroxylase (PHD) inhibitor that displays an IC50 = 2μM in a cell-based assay using a reporter produced by fusing HIF-1α oxygen degradable domain (ODD) to lucifer
MilliporeSigma™ Calbiochem™ TACE Substrate IV, Fluorogenic
An internally-quenched fluorogenic decapeptide substrate that is useful for continuous monitoring of TACE activity and high-throughput screening of TACE inhibitors (kcat =
MilliporeSigma™ Calbiochem™ NFAT Activation Inhibitor III
The NFAT Activation Inhibitor III, also referenced under CAS 3519-82-2, controls the biological activity of NFAT. This small molecule/inhibitor is primarily used for Inflammation/Immunology applications.
MilliporeSigma™ Upstate Human IKKα
Expressed in baculovirus-infected Sf9 insect cell expression system.
MilliporeSigma™ Calbiochem™ SHIP1 Inhibitor, 3AC
The SHIP1 Inhibitor, 3AC controls the biological activity of SHIP1. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ BLM Helicase Inhibitor, ML216
A cell-permeable pyridinyl-thiadiazolylurea compound that selectively blocks Bloom's syndrome protein (BLM) helicase activity of both full-length as well as truncated BLM636-1298 forms (IC50