Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ Glucose Transporter Inhibitor IV, WZB117
The Glucose Transporter Inhibitor IV, WZB117 controls the biological activity of Glucose Transporter.
MilliporeSigma™ Calbiochem™ Sodium Orthovanadate, Activated
A depolymerized vanadate prepared from Sodium Orthovanadate with enhanced ability to competitively inhibit endogenous phosphatases.
MilliporeSigma™ Calbiochem™ 11beta-HSD1 Inhibitor, 10j
The 11beta-HSD1 Inhibitor, 10j, also referenced under CAS 1009373-58-3, controls the biological activity of 11beta-HSD1. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
MilliporeSigma™ Calbiochem™ Autotaxin Inhibitor II, HA130
A thiazolidinedione that is designed to target the ATX active site thr210 with a boronic moiety and shown to potently inhibit ATX lysoPLD activity (IC50 ∽28nM using recombinant human ATX or human plasma) in a reversible manner with a mixed-type Lineweaver-Burk kinet
MilliporeSigma™ Calbiochem™ NMDA Antagonist XI, N1-dansyl-spermine
An N-sulfonyl-polyamine that acts as a potent and more specific antagonist of NMDA receptors expressed in Xenopus oocytes (IC50 = 310, 340nM in NR1/NR2A and NR1/NR2B, respective
MilliporeSigma™ Calbiochem™ Gβγ Modulator II, Gallein
A cell-permeable xanthene compound that binds to Gβγ with high affinity (K
MilliporeSigma™ Calbiochem™ Calpain-1 Substrate, Fluorogenic
An internally quenched fluorogenic substrate peptide derived from the calpain-1 cleavage site of α-spectrin.
MilliporeSigma™ Calbiochem™ Ezh2 Inhibitor III, SAH-EZH2
A helical 27-mer peptide with E54Q modification that directly binds to EDD (Kd = 320 nM) and disrupts protein-protein interaction of EED with EZH2 and EZH1.
MilliporeSigma™ Calbiochem™ Brk Inhibitor, Cpd 4f
A cell permeable, highly potent, and very selective inhibitor of breast tumor kinase (Brk; IC50 = 3.15 nM). Displays anti-proliferative activity against multiple breast cancer cell lines.
MilliporeSigma™ Calbiochem™ RIPK3 Inhibitor, GSK'872
A cell-permeable, selective inhibitor of RIP3-selective kinase with >1,000-fold selectivity over a vast majority of more than 300 other kinases.
MilliporeSigma™ Calbiochem™ L-N5-(1-Iminoethyl)ornithine, Dihydrochloride
A cell-permeable, more potent inhibitor of endothelial nitric oxide synthase compared to other arginine analogs such as L-NAME and L-NMMA.
MilliporeSigma™ Calbiochem™ Vigabatrin
A selective, irreversible inhibitor of GABA transaminase with antiepileptic properties
MilliporeSigma™ Calbiochem™ Aurintricarboxylic Acid
A cell-permeable polyanionic, polyaromatic compound used as a powerful inhibitor of cellular processes that are dependent on the formation of protein-nucleic acid complexes.
MilliporeSigma™ Calbiochem™ InSolution™ Pepstatin A, Synthetic
A 25 μM (10 mg/583 μL) sterile-filtered solution of Pepstatin A, Synthetic in DMSO.
MilliporeSigma™ Calbiochem™ Iron Chelator IV, 21H7
The Iron Chelator IV, 21H7 controls the biological activity of iron-regulated enzymes. This small molecule/inhibitor is primarily used for Cancer applications.